BioServe's Global BioRepository: In-house Samples
With more than 600,000 human tissue, serum, DNA, and RNA samples, from over 120,000 patients on four continents, academic and industry researchers have access to a diverse range of biomaterials in various disease states to meet their research needs.
Our human samples are handled consistently according to validated protocols used at all of our sites. Each human tissue sample is snap frozen to preserve mRNA and protein and is matched with unaffected human tissue, as well as DNA and sera from the donor in most cases. RNA is subjected to rigorous quality control (QC) to monitor degradation. Each human tissue sample is accompanied with:
- Detailed demographic information, including family history for three generations
- Gold standard clinical diagnostic information
- Complete drug history, including adverse events
- Full pathology report, including H& E slides
- Complete phenotypic data.
Human sample types currently in our inventory
Human Tissue (Frozen)
All frozen tissues are snap-frozen upon collection and stored in liquid nitrogen to preserve the integrity of RNA and proteins. Our frozen tissue inventory includes samples from a wide variety of organs, diseases, cancers and adjacent normal tissue.
Human, Formalin-fixed, paraffin-embedded tissue (FFPE)
Our inventory contains more than 12,000 FFPE tissue samples from various diseased and adjacent normal tissues.
Human DNA and RNA
DNA samples from a wide range of diseases and conditions including diabetes, various cardiovascular conditions, obesity, as well as various cancer types such as breast, colon, lung, and prostate cancer. In addition, DNA is available from more than 11,000 disease-free individuals, or controls.Our RNA inventory currently consists of more than 1,000 RNAs from freshly frozen, highly annotated tumor and adjacent normal samples.
Serum samples from several disease types and disease-free normal controls, collected by validated protocols established by the FDA and NCI guidelines for biomarker research.