SNPlates™

Ready-made Case-Control Studies

Screening DNA from disease cases and disease-free controls, also known as the case-control study, is the most common method to identify genetic markers of disease and novel gene targets for treatment.  BioServe has developed SNPlates™ to help researchers cost-effectively validate these markers.

SNPlates™ are pre-aliquotted (180:180) data-rich patient samples to perform case-control studies. These case-control studies on a plate were designed by genetic epidemiologists to identify genetic markers of disease and to validate previously identified genetic markers in specific disease states.

Compare the high cost of traditional case-control studies vs. BioServe's SNPlate solution:

High Cost of Case-Control Studies:

• Specialized personnel such as physicians, epidemiologists, biostatisticians, database developers, interviewers, phlebotomists, IRB coordinators and biorepository managers in order to identify and process samples
• Infrastructure required including laboratories, freezers, LIMS.
• Opportunity cost enormous time required to organize, collect, and prepare samples for analysis

High-Value SNPlate Samples and corresponding Clinical Data:

• Samples mined from BioServe's Global BioRepository of over 120,000 patients with fully annotated DNA samples of various diseases with detailed demographic, smoking, diet, and clinical data
• Cases matched to controls based on age, gender, race and body mass index
• Huge disease population from one of the largest commercial repositories in the world
• All samples have passed rigorous quality control tests including genotyping data for 10 single nucleotide polymorphisms (SNPs)